Which sequence correctly lists the order of the mitosis phases?

• A. Prophase, Metaphase, Anaphase, Telophase
• B. Prophase, Anaphase, Metaphase, Telophase
• C. Metaphase, Prophase, Anaphase, Telophase
• D. Telophase, Prophase, Metaphase, Anaphase

Answer: (A)

The sequence reflects the actual order of events as chromosomes are handled and divided. In the first phase, chromosomes condense and become visible as distinct sister chromatids; the spindle apparatus forms and the nuclear envelope breaks down. Next, chromosomes line up along the center of the cell, known as the metaphase plate, ready for separation. Then the sister chromatids are pulled apart toward opposite poles as the spindle fibers shorten, marking the separation of genetic material. Finally, the chromosomes arrive at the poles, de-condense, and the nuclear envelope re-forms around each set, completing mitosis. Cytokinesis often follows, splitting the cytoplasm to produce two separate daughter cells.

This order makes sense because each step depends on the preceding one: condensation prepares chromosomes for alignment, alignment coordinates even separation, and separation leads to individual nuclei forming at the poles. The other sequences would place events out of place—for example, separating chromatids before they are properly aligned, or starting with a phase where chromosomes are not yet condensed.