Which sequence accurately lists the five epidermal layers from outermost to innermost as recalled by the common mnemonic 'Come, Lets Get Sun Burnt'?

• A. Corneum, Lucidum, Granulosum, Spinosum, Basale
• B. Basale, Spinosum, Granulosum, Lucidum, Corneum
• C. Corneum, Granulosum, Spinosum, Lucidum, Basale
• D. Lucidum, Corneum, Granulosum, Spinosum, Basale

Answer: (A)

Understanding the orderly stack of epidermal layers from the surface inward helps you see why this sequence is correct. The outermost layer is the stratum corneum, made of dead, keratin-filled cells that form the protective barrier. Just beneath it is the stratum lucidum, a thin, clear layer found only in thick skin like the palms and soles. Next comes the stratum granulosum, where keratinization begins and keratin granules accumulate. Then the stratum spinosum, where keratinocytes are connected by desmosomes and continue differentiating. At the deepest level lies the stratum basale, a single row of actively dividing cells that continually generates new keratinocytes. The mnemonic Come, Lets Get Sun Burnt maps precisely onto this order, so this sequence matches the true anatomy. Other sequences misplace lucidum, shuffle the deeper layers, or omit lucidum, which would not reflect how the epidermis is organized.